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MEDRS does not ban primary sources; they can be used occasionally, for example, in cases where only primary sources exist.
The efficacy of ZOLOFT as a treatment for major depressive disorder was established in two placebo-controlled studies in adult outpatients meeting DSM-III criteria for major depressive disorder.
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The more complete data submitted later by the sertraline manufacturer Pfizer indicated increased suicidal behavior.
The conditions and duration of exposure to Sertraline varied greatly, and included (in overlapping categories) clinical pharmacology studies, open and double-blind studies, uncontrolled and controlled studies, inpatient and outpatient studies, fixed-dose and titration studies, and studies for multiple indications, including major depressive disorder, OCD, panic disorder, PTSD, PMDD and social anxiety disorder.
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Warnock CA, Azadian AG: Cross-sensitivity between paroxetine and sertraline.
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PMDD, which is far less common, was officially recognized as a disease in 1987.
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Some SSRI antidepressants such as fluoxetine, paroxetine and sertraline may have an effect on pupil size causing dilation.
The antidepressant action of Sertraline hydrochloride tablets USP in hospitalized depressed patients has not been adequately studied.
You can view the site using your current browser, but certain functions will not be supported and the site may display incorrectly.
Later on came fluvoxamine, citalopram and finally escitalopram.
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Remission rates following antidepressant therapy with bupropion or selective serotonin reuptake inhibitors: a meta-analysis of original data from 7 randomized controlled trials.
To say that sertraline was \"developed during a period when ideas about depression and the proper treatment for it were swinging towards pharmaceuticals\" is incorrect.
In an 8-week head-to-head comparison study, escitalopram and sertraline showed similar efficacy, response rates (75 vs.
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The target audience for this guideline includes all clinicians, and the target patient population includes adults with major depressive disorder.
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However, some people will respond very well to just therapy or just medication.
Due to poor anti-depressive effect of sertraline, the treatment was altered back to fluoxetine.
Symptomatic liver injury probably related to sertraline.
Tell your healthcare provider about all the medicines that you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Qaseem A, Barry MJ, Kansagara D, for the Clinical Guidelines Committee of the American College of Physicians.
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The risk for SSRI-induced sodium depletion appears to be increased during the first few weeks of treatment in women, the elderly, and patients also using diuretics.
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Management should include immediate discontinuation of antipsychotic drugs and other drugs not essential to concurrent therapy, intensive symptomatic treatment and medical monitoring, and treatment of any concomitant serious medical problems.
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Selective serotonin reuptake inhibitors in pregnant women and neonatal withdrawal syndrome: a database analysis.
ZOLOFT should be administered once daily, either in the morning or evening.
WAS significantly better in the high-dose group.
This is an older class of antidepressant drug that typically has significant side effects, and therefore are used less often than SSRIs to treat depression.
Because fluoxetine, citalopram, clomipramine, and sertraline were effective if administered during the luteal phase only, these drugs may be used as first-line therapy and taken intermittently only during the luteal phase.
Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain\".
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After 2 weeks I went to a GP who took a urine sample, swab test of the inside of my penis and a blood test and gave me 2 tablets to take incase of gonerria.
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Based on the pharmacokinetic results, there is no need for dosage adjustment in patients with renal impairment (see CLINICAL PHARMACOLOGY).
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In both conditions, therapy with CPAP eliminates obstructive apneas, as expected, but central apneas may persist.
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Even if you decide to drink alcohol in moderation while you are taking Zoloft, you should be cautious.
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Hello I\'ve been on sertraline for a couple of months and its working great most of the time.
First you say that you \"realize that this is a limited scope article\" but then you still demand \"analysis of the historical context of antidepressant development\".
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Sertraline HCl is marketed by Pfizer as Zoloft; generic Zoloft or Sertraline is manufactured outside of a Pfizer facility; this is the biggest difference between Zoloft and Sertraline.
Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors.
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Conclusions: The preclinical and clinical data show that bupropion acts via dual inhibition of norepinephrine and dopamine reuptake and is devoid of clinically significant serotonergic effects or direct effects on postsynaptic receptors.
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SSRIs and SNRIs, including ZOLOFT, may increase the risk of bleeding events ranging from ecchymoses, hematomas, epistaxis, petechiae, and gastrointestinal hemorrhage to life-threatening hemorrhage.
All events are included except those already listed in the previous tables or elsewhere in labeling and those reported in terms so general as to be uninformative and those for which a causal relationship to sertraline treatment seemed remote.
PTSD is that the medication of choice, serotonin re-uptake inhibitors, take several weeks before they show considerable effects on PTSD symptoms.
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From personal experience (I am unsure who should be credited with this info; it is reported on various websites as well), during the \"insomnia\" phase while my body was adapting to its use (apparently), I would wake up very sweaty, from the first night I took it and decreasing afterward.
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Conversely, the exclusion of children and teens with major depression and pervasive developmental disorders may have limited the generalizability of the results to these populations.
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Lustral\" in the lead, I\'ve added a footnote stating \"Medication trade names may differ between countries.
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